Rheumatoid Arthiritis

The Story of isobutylphenyl propionic acid
Introduction
Rheumatoid Arthritis is an autoimmune disease; this is when the bodys immune system fails to distinguish between self and non self tissues. Therefore the body starts to attack and destroy its own tissues causing many complications. People suffering from Rheumatoid Arthritis suffer from traumatic inflammation (swelling of tissues that become warm) of and damage to the cartilage and bone of the joints which leads to vain and deformed joints. The disease usually starts in the wrists, hands or feet and can spread to other parts of the body. The main derivation of treatment for Rheumatoid Arthritis is the use of Ibuprofen.
Ibuprofen is a propionic acerb derivative; there are many different types of propionic acid, just they function differently to Ibuprofen. Propionic acid derivatives are classified as NSAID (Non-steroidal anti- inflammatory drugs). Ibuprofen consists of anti-inflammatory (reduction of inflammation), analgesic (to lessen or relieve pain) and antipyretic (prevention of fever) properties. It is used for different types of pain, inclination from; rheumatic diseases, musculoskeletal disorders, mild to moderate pain including dysmenorrhoea (menstrual pain), migraine, alveolar consonant pain, fever with discomfort and pain in children and post immunisation pyrexia.



(BNF)
Pain, fever and inflammation are stimulated by the anaesthetize of a chemical known as prostaglandins in the body. Ibuprofen is an NSAID which is believed to work by inhibiting prostaglandin synthesis. Cyclooxygenase (COX) is the main enzyme for the biogeny of prostaglandin. It exists in two forms of isomers; constitutive COX-1 and the inducible COX-2. COX-1 is responsible for the physiological functions whereas COX-2 is involved in inflammation; thusly the inhibition of COX explains both the therapeutic and side personal effects of NSAIDs. For this reason NSAID which selectively inhibit COX-2 has a greater anti-inflammatory efficacy combined with less toxicity. In...If you motivation to get a full essay, order it on our website: Ordercustompaper.com



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